Endocrine Abstracts

Introduction and objective: Cardiovascular mortality is high in acromegaly. Our aim in this study was to determine the levels of the new cardiovascular marker in active acromegaly patients, the mean platelet volume (MPV) values before and after octreotide acetate long-acting repeatable treatment.Material and methods: Thirty-six patients with active acromegaly who presented at the Endocrinology Department (mean age 46.0±14.0 years and mean BMI: 30.4&...

Aim: Hashimoto’s thyroiditis (HT) is an autoimmune disease in which a breakdown of immune tolerance is caused by interplay of a variety of immunologic, genetic, and environmental factors. Mean platelet volume (MPV) is the measure of platelet size. MPV possibly is a simple way to estimate platelet activity. Activated platelets play an important role in the pathogenesis of vascular disease especially coronary heart diseases. Larger platelets are metabolically and enzymatica...

Introduction and objective: Platelets play an important role in the development of thrombotic events. Increase of mean platelet volume (MPV) may indicate pre-thrombotic conditions as a new cardiovascular marker. Larger platelets have been reported to be metabolically more active than smaller ones. Our aim of present study is to evaluate MPV levels in patients with papillary thyroid cancer.Materials and methods: Forty-seven patients with newly diagnosis m...

Purpose: The aim of this study was to evaluate the association and frequency of thyroid autoimmunity in patients with empty sella syndrome and to evaluate the possible effects of thyroid auto-antibodies on clinical and laboratory findings in patients with empty sella syndrome.Materials and methods: We recruited 93 patients (female) and 22 male patients (mean age 55.51±14.82) who were admitted to the Endocrinology Clinic of Erzurum Regional Training ...

Purpose: The purpose of this study were to evaluate the relation thyroid autoimmunity and euthyroid hashimoto thyroiditis in patients diagnosed with pituitary adenoma and association of pituitary adenoma with clinical and laboratory findingsMaterials and methods: The retrospective study population included a total of 230 participants. A total of 189 patients (67 with prolactinoma, 35 with acromegaly, 4 with cushing disease and 83 with non-functional pitu...

Aim and objective: Mucormycosis is a rare life-threatening fungal infection. Immunocompromised patients are often affected. We report a rare diabetic patient with pancreatic adenocarcinoma who was presented diabetic ketoacidosis and rhino-orbito-cerebral mucormycosis.Case presentation: A 66 years old man with pancreatic adenocarcinoma and type 2 diabetes mellitus was presented diabetic ketoacidosis and severe infection of the facial sinuses, orbita, and ...

Aim and objective: Mucormycosis is a rare life-threatening fungal infection. Immunocompromised patients are often affected. We report a rare diabetic patient with pancreatic adenocarcinoma who was presented diabetic ketoacidosis and rhino-orbito-cerebral mucormycosis.Case presentation: A 66 years old man with pancreatic adenocarcinoma and type 2 diabetes mellitus was presented diabetic ketoacidosis and severe infection of the facial sinuses, orbita, and ...

Objective: Treatment of diabetic foot ulcer is complex and difficult. Blood glucose regulation, debridment and surgical revascularization are used in management of diabetic foot ulcer. Intralesional Epidermal Growth Factor (EGF) is a new treatment approach for diabetic foot ulcer. We report our experience with eight patients with diabetic foot ulcer who were treated by intralesional EGF.Patients and methods: A total of eight patients whose diabetic foot ...

Objective: Diet, lifestyle changes, medical agents and surgical approaches are treatment options in obese patients. We reported two morbid obese patients who lost 25 and 21% of their previous weight respectively with only lifestyle changes and orlistat therapy.Case 1: Forty nine year-old woman had type 2 diabetes mellitus for 20 years. She took premix insulin twice a day. Her height was 157 cm, her weight was 120 kg, body mass index was 48.6 kg/m2</...

Introduction and aim: Overt thyroid dysfunction is well recognized to affect weight, but the influence of minor perturbations of thyroid function remains unclear. There is ongoing debate regarding the influence of minor changes in thyroid hormones status within the normal range and BMI. The aim of this study was to investigate the association between thyroid function within normal ranges and obesity via BMI and body compositions analyzed by bioelectrical impedance.<p class...